-
사진
유용한 해양생물 이야기 이미지
-
지식채널
-
논문정보
검색결과 3건
논문정보 목록 - 제목, 내용, 저자, 저널명/발행자, 상세보기 제목 내용 저자 저널명/발행자 상세보기 Investigation of ${alpha}$ -Glucosidase Inhibitory Activity of Ethanolic Extracts from 19 Species of Marine Macroalgae in KoreaIn the present work, we have collected 19 species of macroalgae (9 Phaeophta and 10 Rhodophyta) f rom all around of Korea: Dictyopteris divaricata, D. prolifera, Myelophycus cavus, Papenfussiella kuromo, Petalonia zosterifolia, Petrospongium rugosum, Rugulopteryx okamurae, Sargassum fulvellum, S. muticum, Callophyllis japonica, Gloiopeltis tenax, Gracilaria longissima, Gracilaria vermiculophylla, Grateloupia asiatica, Grateloupia lanceolata, Grateloupia sparsa, Grateloupia turuturu, Grateloupia sp, and Polyopes affinis. The macroalgal species were extracted by 70% ethanol (EtOH) for 24 h and evaluated its inhibitory effects on ${alpha}$ -glucosidase. Among ethanol extracts, Myelophycus cavus showed the most effectively inhibitory activity ($IC_{50}$ , 2.17${mu}g/ml$ ) against${alpha}$ -glucosidase, followed by Sargassum fulvellum (<$IC_{50}$ , 8.13${mu}g/ml$ ), Dictyopteris prolifera ($IC_{50}$ , 16.66${mu}g/ml$ ), Rugulopteryx okamurae ($IC_{50}$ , 50.63${mu}g/ml$ ), and Petrospongium rugosum ($IC_{50}$ , 101.62${mu}g/ml$ ). Furthermore, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay showed no cytotoxicity on mouse pre-adipocytes cell line (3T3-L1). These results suggest that some edible macroalgae merit further evaluation for clinical usefulness as anti-diabetic functional foods.Jeong, So-Young,Qian, Zhong-Ji,Jin, Yeong-Jun,Kim, Gi-Ok,Yun, Pil-Yong,Cho, Tae-Oh Korean Society of Pharmacognosy 상세보기 Investigation of ${\alpha}$ -Glucosidase Inhibitory Activity of Ethanolic Extracts from 19 Species of Marine Macroalgae in KoreaIn the present work, we have collected 19 species of macroalgae (9 Phaeophta and 10 Rhodophyta) f rom all around of Korea: Dictyopteris divaricata, D. prolifera, Myelophycus cavus, Papenfussiella kuromo, Petalonia zosterifolia, Petrospongium rugosum, Rugulopteryx okamurae, Sargassum fulvellum, S. muticum, Callophyllis japonica, Gloiopeltis tenax, Gracilaria longissima, Gracilaria vermiculophylla, Grateloupia asiatica, Grateloupia lanceolata, Grateloupia sparsa, Grateloupia turuturu, Grateloupia sp, and Polyopes affinis. The macroalgal species were extracted by 70% ethanol (EtOH) for 24 h and evaluated its inhibitory effects on ${\alpha}$ -glucosidase. Among ethanol extracts, Myelophycus cavus showed the most effectively inhibitory activity ($IC_{50}$ , 2.17${\mu}g/ml$ ) against${\alpha}$ -glucosidase, followed by Sargassum fulvellum (<$IC_{50}$ , 8.13${\mu}g/ml$ ), Dictyopteris prolifera ($IC_{50}$ , 16.66${\mu}g/ml$ ), Rugulopteryx okamurae ($IC_{50}$ , 50.63${\mu}g/ml$ ), and Petrospongium rugosum ($IC_{50}$ , 101.62${\mu}g/ml$ ). Furthermore, MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay showed no cytotoxicity on mouse pre-adipocytes cell line (3T3-L1). These results suggest that some edible macroalgae merit further evaluation for clinical usefulness as anti-diabetic functional foods.Jeong, So-Young,Qian, Zhong-Ji,Jin, Yeong-Jun,Kim, Gi-Ok,Yun, Pil-Yong,Cho, Tae-Oh The Korean Society of Pharmacognosy 상세보기 B16F10 세포에서 연두털말 에탄올 추출물의 멜라닌 생성 저해효과 To test the possibility of natural cosmetic material, the antioxidant activity using DPPH method and whitening effect for the ethanol extract of a brown alga, Papenfusiella kuromo were examined. In particular whitening effects were estimated by melanin production of B16F10 melanoma cells and confirmed by tyrosinase gene expression in terms of RT-PCR and western bolt analyses. Present results revealed that DPPH radical scavenging activity for P. kuromo extract was about 64% at 50 μg/mL. As compared to IBMX treatment, melanin production of melanoma cells was remarkably inhibited up to 94% at 50 μg/mL of the extract. RT-PCR and western blot analyses showed that the tyrosinase gene expression of the B16F10 cell decreased in a concentration-dependent manner. Especially, antimelanogenic effect at 50 μg/mL of P. kuromo extract was greater than that in the control of Kojic acid treatment, suggesting that the P.kuromo ethanol extract could be a good candidate of whitening agents. Thus, further research on pure chemical isolation of the natural whitening cosmetic materials from P. kuromo extract is required. 박서경,정유헌,박종군,김수정,정대현,최한길 한국미용학회 상세보기 -
특허정보
검색결과 2건
특허정보 목록 - 제목, 등록/출원번호, 출원인, 원문정보 제목 등록/출원번호 출원인 원문정보 연두털말 추출물 또는 분획물을 유효성분으로 포함하는 항균 조성물 1020140074313 원광대학교산학협력단 원문정보 연두털말 추출물을 함유하는 피부외용제 조성물 1020120105771 재단법인 전남생물산업진흥원|주식회사 바이오에프디엔씨|최한길|화순군 원문정보 -
유용한 해양생물 이야기
검색결과 1건
유용한 해양생물 이야기 목록 - 학명, 국명, 생리활성, 원료등록, 특징/이용 학명 국명 생리활성 원료등록 특징/이용 Papenfussiella kuromo 연두털말 항산화, 항염증 화장품원료 등록 화장품원료 등재
-